Description
EDTA WB, NA, Fasting or Non Fasting: As suggested by doctor
Sample Required:
The Coombs Test – Indirect (ICT) requires a small sample of blood. The sample is typically collected through a routine blood draw from a vein in the arm.
Test Time:
The Coombs Test – Indirect (ICT) itself is relatively quick, usually taking a few minutes to collect the blood sample. However, the test results may take longer to process, typically within a few hours to a couple of days, depending on the laboratory and healthcare facility.
ICT Test Normal Range:
The Coombs Test – Indirect (ICT) does not have a specific normal range. The test measures the presence and amount of antibodies in the blood, which can vary depending on the individual and specific circumstances.
What is the test?
The Coombs Test – Indirect (ICT) is a blood test that detects the presence of antibodies directed against red blood cells. It is primarily used to determine if a person has antibodies that can cause immune-mediated destruction of their own red blood cells, a condition known as autoimmune hemolytic anemia. The test is also used to determine blood compatibility for blood transfusions or assess the risk of hemolytic disease of the newborn.
Test Procedure:
During the Coombs Test – Indirect (ICT), a blood sample is collected from a vein in your arm using a needle. The blood sample is then processed in the laboratory to separate the serum, which contains antibodies. The serum is mixed with red blood cells of known characteristics, and if the antibodies are present, they will bind to the red blood cells, causing agglutination or clumping.
When to take the test?
The Coombs Test – Indirect (ICT) may be ordered by a healthcare provider when there is suspicion of an autoimmune hemolytic anemia, such as when an individual has symptoms of anemia, jaundice, or an enlarged spleen. It is also commonly performed during pregnancy to assess the risk of hemolytic disease in the newborn.
Who should take this test?
Individuals who have symptoms suggestive of autoimmune hemolytic anemia or are at risk of hemolytic disease of the newborn may be advised to take the Coombs Test – Indirect (ICT). It is typically ordered by healthcare providers, such as hematologists, obstetricians, or pediatricians, based on the specific clinical situation.
Precautions for exceptional cases (pregnancy, etc.):
For pregnant individuals, the Coombs Test – Indirect (ICT) may be performed to assess the risk of hemolytic disease in the newborn. It is important to discuss any pregnancy-related concerns or conditions with your healthcare provider before undergoing the test.

