Description
Serum, Sex hormone-binding globulin (SHBG) produced by the liver helps to transport biologically inactive forms of hormones such as testosterone, estradiol, and dihydrotestosterone into the bloodstream. Changes in its levels may have an effect on the amount of hormone available to the body. SHBG test is used for the evaluation of androgen deficiency or excess. Increased SHBG may be associated with liver disease, hyperthyroidism, hormone replacement therapy, oral contraceptives, and fertility issue. Deficiency is observed in metabolic syndrome, polycystic ovary syndrome, hypothyroidism, and Cushing syndrome., Non Fasting
Sample Required:
A blood sample is required for SHBG testing. This sample is typically collected from a vein in your arm.
Test Time:
Results for SHBG testing are usually available within a few days to a week, depending on the laboratory’s processing time.
Test Normal Range:
Normal reference ranges for SHBG can vary between labs, but they generally fall within 10 to 50 nanomoles per liter (nmol/L).
What is the Test:
Sex Hormone Binding Globulin (SHBG) is a protein produced by the liver that binds to certain hormones, including testosterone and estradiol (a form of estrogen). This test measures the concentration of SHBG in the blood.
Test Procedure:
A healthcare provider will collect a blood sample from a vein in your arm using a needle and a collection tube. A blood sample is delivered to a laboratory for testing. An automated analyzer in the laboratory detects the concentration of SHBG in the blood.
When to Take the Test:
SHBG testing is often ordered as part of hormone level assessments. It may be performed if there are concerns about hormonal imbalances, such as in cases of polycystic ovary syndrome (PCOS) or androgen excess.
Who Should Take This Test:
Individuals who may benefit from SHBG testing include those with suspected hormonal imbalances or those undergoing evaluation for conditions like PCOS.
Precautions for Exceptional Cases (Pregnancy, etc.):
SHBG testing is typically not affected by pregnancy or other exceptional cases. However, it’s essential to discuss any specific concerns with your healthcare provider.

